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Division of Endocrinology & Metabolism

Noteworthy Publications

Members of the Division of Endocrinology & Metabolism published 31 peer-review articles this past year. Key publications include:

Ma, L, Dong, F, Denis, M, Feng, Y, Wang, MD, Zha, X. Ht31, a protein kinase A anchoring inhibitor, induces robust cholesterol efflux and reverses macrophage foam cell formation through ATP-binding cassette transporter A1. J Biol Chem 2011: 286(5):3370-8

Molgat, ASD, Gagnon, A, Sorisky, A. Macrophage-induced preadipocyte survival depends on signaling through Akt, ERK1/2, and reactive oxygen species. Exp Cell Res 2011; 317(4):521-530

Wang, GS, Kauri, LM, Patrick, C, Bareggi, M, Rosenberg, L, Scott, FW. Enhanced islet expansion by beta-cell proliferation in young diabetes-prone rats fed a protective diet. J Cell Physiol 2010; 224(2):501-8

Gavin, C, Sigal, RJ, Cousins, M, Menard, ML, Atkinson, M, Khandwala, F, Kenny, GP, Proctor, S, Ooi, TC, Diabetes Aerobic and Resistance Exercise (DARE) trial investigators. Resistance exercise but not aerobic exercise lowers remnant-like lipoprotein particle cholesterol in type 2 diabetes: a randomized controlled trial. Atherosclerosis 2010; 213(2):552-7

Shea, AK, Shah, BR, Clark, HD, Malcolm, J, Walker, M, Karovitch, A, Keely EJ. The effectiveness of implementing a system into routine clinical practice — does it increase postpartum screening in women with gestational diabetes? Chronic Dis Can 2011;31(2):58-64

 

 

Key Grants

Sorisky, A. CIHR. Atherogenic adipocyte dysfunction induced by TSH

Scott, F. CIHR. Mechanisms of gut involvement in dietary protection from autoimmune diabetes

Zha, X. HSFO. Characterization of microparticles released by ABCA1-expressing macrophages

Keely E. Public Health Agency of Canada/Canadian Diabetes Strategy. Enhancing best practices to improve screening and risk reduction in the antenatal and postpartum care of women with gestational diabetes

Lochnan, H. University of Ottawa—AIME. Power asymmetries between residents and faculty limit the reporting of professional lapses: A participatory strategy to promote awareness and evaluation of professionalism in the Faculty of Medicine. Principal Investigator

 

Overview

The Division of Endocrinology and Metabolism is based at the Riverside campus of The Ottawa Hospital. Our 4th floor location was completely renovated in 2004, and now encompasses administrative offices, conference/teaching rooms, a spacious ambulatory clinic area, and a contiguous clinical research centre that includes its own clinical assessment rooms, a wet bench clinical research laboratory, as well as a dynamic endocrine testing laboratory. Our basic, translational, and clinical research activities are linked to the Chronic Disease Program of the Ottawa Hospital Research Institute (OHRI), and include studies addressing adipose tissue dysfunction, lipoprotein metabolism, gestational diabetes, autoimmunity in type 1 diabetes, and innovative models of quality and safety for diabetes care.

Our ambulatory clinic area is organized as the Foustanellas Endocrine and Diabetes Centre, and is the leading referral centre in Eastern Ontario for complex clinical care, research, and professional education. We serve a population of just over a million people, providing specialized bilingual, inpatient and outpatient care to patients and families with a variety of endocrine and metabolic conditions including diabetes, lipid disorders, thyroid cancer, osteoporosis, and disorders of the thyroid, the parathyroid, the pituitary, and the adrenal glands.

Research

Our research activities, linked to the Chronic Disease Program of the OHRI and the University of Ottawa, are led by clinicians and basic scientists. They span a wide range of investigations, from biomedical translational studies to clinical research trials to models of health care delivery.

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Education

We provide outstanding postgraduate and undergraduate education opportunities. The fellowship program in Endocrinology and Metabolism at the University of Ottawa provides you with a dynamic, stimulating environment with a strong focus on residency education. A large catchment area ensures exposure to all types and severity of endocrine disease. Our program offers many diverse opportunities for domestic and visiting clerkship students interested in the field of endocrinology, ranging from outpatient clinical endocrinology to consultation services.  Furthermore our elective opportunities can accommodate students at varying levels of training.

Patient Care

The Division of Endocrinology and Metabolism provides specialized inpatient and outpatient care for a population of just over one million people. The Foustanellas Endocrine and Diabetes Centre, located at the Riverside Campus, is the major referral centre for Eastern Ontario. There are approximately 20,000 patient visits per year for a wide variety of endocrine and metabolic conditions and complex diabetes care.

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