Kudos for August 2012



Frank Molnar was profiled in The Ottawa Citizen, July 23rd edition, as one of the co-authors of a report commissioned by the Alzheimer Society of Ontario entitled Dementia Evidence Brief. The report claims that dementia cases are expected to rise – “1 in 5 Eastern Ontario seniors could suffer from dementia over the next decade”

David A. Grimes was featured on CBC TV in late July for leading an initiative to create national clinical guidelines that aid family physicians and other health-care professionals to diagnose and treat Parkinson’s disease.

Carl van Walraven interviewed by Ottawa Citizen in “Hospital wins right to withhold heroic measures from 90-year-old car crash victim” case.  Dr. van Walraven presented to the Consent and Capacity Board panel.

Andrew Wielgosz interviewed by John Gormley Live – Newstalk 650 about his new Canadian led study which reported that people who work shift work have an increased risk of heart attack and stroke.

Michael Rudnicki appeared on CTV’s news channel to talk about whole-genome sequencing. He spoke of the promise it holds for improving personalized therapies that target the unique genetic make-up of cancer tumours.

John Bell and Rebecca Auer appeared on CBC TV discussing their recent work on an oncolytic virus vaccine that harnesses the immune system to fight cancer. Paper in Molecular Therapy has details.

Jeff Turnbull wrote to Ottawa Citizen on behalf of the homeless in Canada – “We must not let the need for prudent fiscal management make this a lesser nation”.  Canada must defend the most vulnerable.

Mark Tyndall in the news several times concerning the cuts to refugee health program and the first take home HIV test.

Alan Forster participated in a news conference at uOttawa’s Health Sciences Library where Federal Health Minister, Leona Aglukkaq, announced $239 M over 3 years to fund the Canadian Institute for Health Information.


Carl van Walraven and Al Forster have developed a new score for assessing the risk of a patient dying or requiring urgent readmission within 30 days of discharge from hospital.  For details see two articles in Open Medicine.

Michael Rudnicki and his team have discovered a unique pair of proteins that turn on a genetic switch telling a muscle stem cell to become a committed muscle cell.  Understanding this mechanism has potential for therapies to help muscle-wasting diseases. See Cell Stem Cell for details.

Jeremy Grimshaw and a team from Quebec have studied the overuse of antibiotics for acute respiratory infection. The study shows that training to enhance the patient’s role in decision-making resulted in a reduction of antibiotic prescriptions for respiratory infections. Physicians in the trial who used the training program, DECISION+2 issued fewer prescriptions and after 2 weeks, outcomes were comparable to control group. See CMAJ for details.

Mark Clemons published results from a clinical trial which refined the appropriate dosing interval of a drug commonly used to combat bone damage in breast cancer that has spread to the bone.  The study found that administering pamidronate less frequently (once every 12 weeks) in women with a low risk form of the condition was as effective as administering every 3-4 weeks. See details in American Journal of Clinical Oncology.

Mark Clemons and colleagues have developed the world’s first tool to predict whether cancer patients are likely to suffer from chemotherapy-induced nausea and vomiting. The tool assigns each patient a numerical score based on risk factors (age, type of chemo, type of cancer, other meds, previous morning sickness during pregnancy) See Journal of Supportive Oncology for details.


Shawn Aaron has received $75,000 from Cystic Fibrosis Canada to study why acute viral infections worsen the chronic bacterial infections found in the lungs of patients with CF.

Christina Addison has received $150,000 from Prostrate Cancer Canada to explore the spread of prostrate cancer to bone.

Luc Sabourin has been awarded $450,000 from the Canadian Breast Cancer Foundation to continue his exploration of how novel proteins might effectively reduce the movement of breast cancer cells.

CIHR Operating Grants March 2012

ALBERT, Paul R: Coupling domains of hte 5-HT1A receptor

ANGEL, Jonathan B: Regulation and Function of Soluble IL-7 Receptor Alpha (CD127) in HIV Infection

COLAVITA, Antonio: Understanding VANG-1/Van Gogh and PRKL-1/Prickle function during neurite growth inhibition in C. elegans

RUDNICKI, Michael A: Genetic Regulation of Myogenesis

SLACK, Ruth S: The role of the Rb-E2F pathway in adult neurogenesis

WELLS, Philip S: New Oral Anticoagulants for the Prevention of Venous Thromboembolism in High-Risk Ambulatory Cancer Patients: A Randomized Placebo-Controlled, Double-Blind Clinical Trial

CIHR Dissemination Events – Priority Announcements – Ethics

FOREMAN, Thomas: 2012 Champlain LHIN Ethics Education Program Scholarships

Greg Knoll also received a CIHR grant for ‘Analyzing health databases to improve treatment of kidney disease.

Dean Fergusson received a CIHR grant for ‘ Blood thinners for treatment of septic shock”.

David Picketts has been awarded a $300,00 grant from the Foundation Fighting Blindness to investigate the development of retinal nerves and how they work as a network to transmit signals from the eye’s photoreceptors to the brain.


Marc Carrier has received a $300,000 New Investigator Award from HSF to investigate a novel cancer screening strategy for people with unexplained venous blood clots.